Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC363H588N86O94S3

DescriptionStandard

        MEQLALELVASLGLSVETAYAVIRMVMAGTSIWSIIGIILASGGIIGIGYATLVYLIKRKLKEWSFKAVAAW
    

Molecular Weight7757.27 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)1.50

Net Charge (pH 7.4) 1.27

Charge Density (pH 7.0) 0.0209

GRAVY Index1.01

Hydrophobic Moment 0.59

Boman Index0.41

Instability Index15.09

Aliphatic Index 140.97

Aromaticity 0.0972

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 20970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2839.72

LogP -14.37

H-bond Donors 103.0

H-bond Acceptors 99.0

Rotatable Bonds 258.0

Heavy Atoms 546.0

Ring Count 10.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0097568 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus sp. sptzw28 [Bacterium]

FamilyBacteriocin

Tax ID715179

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal