Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length462 amino acids

Chemical FormulaC2337H3702N632O655S10

DescriptionStandard

        TNPGFVVRITQAGLDYAHQHGIAILEKELAQLKLPDISGDSRVGRVGKVRYELSRLRLRDFHLPYSRITPISNVGLQVSISNAFAELDGDWRVKFLFVRDHGSFDLKVENVYIKISLRLGSDARGKPTVSTSECRTRISKVRVLFSGKLGWLYNLFHSVIESRFRKILEDKVCDIVEKSVHNELQTYVQTLPVTAKIDAKTGIDYSLVAPPRATAQSLDADLKGEFYSLAHRSTVPFSPLPLAFPSDHDRMVYFGASSYFFNTAGIAYHEAGALVFEVTQDMAILSLQIPKEAGFSLNTSIFSAFIPQLEEMYPNMPMKFRLSTPTAPFLTIGPGGISLRPIVEAQAYAILPNSSLAPLFLLSLVRNVSAVINVRSGHLVGSLDVGRIRLSLKDSAVGTFQVRMMQSLMNILTSSTLLPRLNARLDEGFPLPLPDRIQLSNILVRFYQNFLLLGADVHFQPR
    

Molecular Weight51452.88 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)9.38

Net Charge (pH 7.4) 8.51

Charge Density (pH 7.0) 0.0203

GRAVY Index0.07

Hydrophobic Moment 0.64

Boman Index0.09

Instability Index34.18

Aliphatic Index 103.81

Aromaticity 0.0931

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 31985.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0106480 VERIFIED: NO

Provenance & Taxonomy

OrganismPlatysteira castanea [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria