‹ ›
MYP_119816
← PREVIOUS NEXT → BACK
Basic Information
Defensin DefMT6
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
38 amino acids
C175H283N61O49S6
Standard
Sequence
GFGCPLNQGACHNHCRSIKRRGGYCSGIIKQTCTCYRK
Physicochemical Analysis
4217.89 Da
9.55
6.87
6.47
0.1808
-0.60
0.68
-0.18
74.60
43.68
0.0789
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1807.99
-24.05
71.0
64.0
140.0
291.0
6.0
41.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0224662 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus,Ixodes scapularis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-Gram-positive Antibacterial Antifungal Antimicrobial Antiparasitic Antiprotozoal
Listeria fleischmannii DSM 24998
1 μM
MIC
PMID26255244;27822206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
RECORD: Rec_0227283 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus,Ixodes scapularis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-Gram-negative Antibacterial Antifungal Antimicrobial Antiparasitic Antiprotozoal
Pseudomonas aeruginosa DSM 50071
2 μM
MIC
PMID26255244;27822206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
RECORD: Rec_0264667 VERIFIED: YES
Provenance & Taxonomy
Ixodes scapularis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-Gram-negative Antibacterial Antimicrobial
Escherichia coli TOP10
3.46 OD_ID
MeX pooled growth assay (OD_ID at 4.5 h)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0275178 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-Gram-negative Antibacterial Antifungal Antimicrobial Antiparasitic
Gram- Pseudomonas aeruginosa
2 μM
MIC
PaperIxodes ricinus defensins attack distantly-related pathogens. PMID26255244
RECORD: Rec_0294992 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus,Ixodes scapularis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-Gram-positive Antibacterial Antifungal Antimicrobial Antiparasitic Antiprotozoal
Staphylococcus aureus DSM 2569
2 μM
MIC
PMID26255244;27822206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
FIRST PREV 1 2 3 4 5 NEXT LAST
Showing 5 records · Page 3 of 5