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MYP_119816
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Basic Information
Defensin DefMT6
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
38 amino acids
C175H283N61O49S6
Standard
Sequence
GFGCPLNQGACHNHCRSIKRRGGYCSGIIKQTCTCYRK
Physicochemical Analysis
4217.89 Da
9.55
6.87
6.47
0.1808
-0.60
0.68
-0.18
74.60
43.68
0.0789
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1807.99
-24.05
71.0
64.0
140.0
291.0
6.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0131601 VERIFIED: YES
Provenance & Taxonomy
Malpighian tubules [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
Staphylococcus aureus
2 μM
MIC
PaperIxodes ricinus defensins attack distantly-related pathogens.
RECORD: Rec_0132774 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus,Ixodes scapularis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Fusarium graminearum 8/1
2 μM
IC50
PMID26255244;27822206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
RECORD: Rec_0155151 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
DefM
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiparasitic
PaperDev Comp Immunol. 2015 Dec;53(2):358-65. | https://www.ncbi.nlm.nih.gov/pubmed/26255244 PMID26255244 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
RECORD: Rec_0166621 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]; Arthropoda [Animal]
9940; 6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID26255244 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
RECORD: Rec_0189961 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus,Ixodes scapularis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Fusarium culmorum
12 μM
IC50
PMID26255244;27822206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
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