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MYP_119787
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Basic Information
U5
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-Influenza A virus
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Standard
20 amino acids
C105H158N34O27S
Standard
Sequence
IPLRGAFINGRWDSQCHRFS
Physicochemical Analysis
2360.65 Da
10.26
1.84
1.57
0.0919
-0.47
0.49
-0.09
62.12
63.50
0.1500
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1001.54
-9.97
37.0
31.0
74.0
167.0
6.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0073608 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-Influenza A virus Replication inhibition
Influenza A virus (H1N1) | MDCK cells
5.465 μM
IC50
Mammalian: 20 h; Yeast: 30 min; E. coli: >10 h
PaperFusion-inhibition peptide broadly inhibits influenza virus and SARS-CoV-2, including Delta and Omicron variants. | Zhao H, Meng X, Peng Z, Lam H, Zhang C, Zhou X, Chan JF, Kao RYT, To KK, Yuen KY. | Emerg Microbes Infect. 2022 Dec;11(1):926-937. | DOI:10.1080/22221751.2022.2051753 | PMID:35259078 PMID35259078 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35259078/
RECORD: Rec_0113883 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PMID35259078 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35259078/
RECORD: Rec_0318239 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
influenza A virus(H1N1):inhibition of viral replication in MDCK cells
12.9 μg/mL
IC50
PMID35259078 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35259078/
RECORD: Rec_0330125 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ponericin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
H1N1
PMID35259078 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35259078/