Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length506 amino acids

Chemical FormulaC2512H4028N642O715S18

DescriptionStandard

        MSLTFSFRMHCFQSNEDIGRERLVLKKTAALVKMYPCCWLILVALIPVTLGTNPGVNVKLTRKGLEYGRQLGLASIQQELKSIKIPDISGTERVFPIGKVQYSLSNLQIVNVGFPQSAVDLVPGTGVRLSISNAFFSLHGDWRVKYLVIIKDSGSFDLNVNGLTITTSIAIRSDETGRPAVSSVGCAASVGSVSIKFHGGASWLYNLFTSFIDKALRDEVAKKLCPLVNNAVSNLNPHLKTLNVLAQVDKYAEIEYSMVSSPTVSSSSIDLNLKGEFYNIGKHQEPPVSPTLFSLPSQNNNMLYMGLSAFTANSAAFVYDKAEVFNLYITDDIIPQSSPIRLNTKSFGIFIPQIAKLYPGLMIKLLVKTVKTPIISFQPNNITIQATGTVTAYAIQPTAILSPLFVLNLGTSVSTQMFVTEMRLAGAVSLNKMDLTLGTSYVGAFQVKSLDKVLRTVLELVVIPKVNAQLAKGYPLPAFGKMKLVNTQLQVLKDYMLIGTDVQFMA
    

Molecular Weight55239.89 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)13.90

Net Charge (pH 7.4) 13.25

Charge Density (pH 7.0) 0.0275

GRAVY Index0.25

Hydrophobic Moment 0.83

Boman Index0.17

Instability Index33.80

Aliphatic Index 107.45

Aromaticity 0.0850

Extinction Coeff. Reduced 40340.00

Extinction Coeff. Oxidized 40590.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0348868 VERIFIED: NO

Provenance & Taxonomy

OrganismChanna argus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria