Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length498 amino acids

Chemical FormulaC2429H3913N617O707S20

DescriptionStandard

        MRLPSPFALPLSSPTDTSGETASVKMFLCCWLALVALIPMTLGTNPGVEVKLTEKGLEYGRQLGMTSILQKLKTIKVPDISGSQEVSPIGKVEYSLSNMQIVDVGLPKSALDLVPGTGVRLSIGNAFIHLQGNWRVKYIKIIKDSGSFDLNVNDLAITTSIAIKSDETGRPVVSSVSCSATVGSASIRFHGGASWLYNLFKDFIDKALRNALQKQICPLVADAVSDLNPHLKTLNVVAKVDQYAEIEYSMVSSPTVSNSSVDLSLKGEFYNIGKHQEPPFSPAAFSLPPQINNMLYIGVSVFTTNSAAFVYNTAGALSLYITDDMIPQGSPIRLNTRTFGAFIPQIAARFPGLMMKLLVKTVKSPVITFEANNVTVQATGTVTAYAIQANATLSPLFVLNLETSVTVQLFVSEMRLAGAVTLNKMDLTLGTSYVGEFQVKSLDSILQMVIKVVVIPKVNVQLAKGYPLPTLGKMKLVNTQLQVLKGYMLIGTDVQFMG
    

Molecular Weight53713.06 Da

Isoelectric Point (pI)9.00

Net Charge (pH 7.0)6.83

Net Charge (pH 7.4) 6.25

Charge Density (pH 7.0) 0.0137

GRAVY Index0.27

Hydrophobic Moment 0.78

Boman Index0.18

Instability Index30.32

Aliphatic Index 105.84

Aromaticity 0.0743

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37610.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0320416 VERIFIED: NO

Provenance & Taxonomy

OrganismPerca fluviatilis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria