Peptide Database

Peptide NameT-142

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV

Antiviral ▸ Anti-Pneumovirus ▸ Anti-RSV

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC178H300N46O57S

DescriptionStandard

        YTSVITIELSNIKENKCNGTDAKVKLIKQELDKYK
    

Molecular Weight4028.63 Da

Isoelectric Point (pI)8.87

Net Charge (pH 7.0)1.75

Net Charge (pH 7.4) 1.51

Charge Density (pH 7.0) 0.0501

GRAVY Index-0.67

Hydrophobic Moment 0.58

Boman Index-0.16

Instability Index31.75

Aliphatic Index 97.43

Aromaticity 0.0571

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1735.33

LogP -16.54

H-bond Donors 60.0

H-bond Acceptors 60.0

Rotatable Bonds 145.0

Heavy Atoms 282.0

Ring Count 2.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0257832 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman orthopneumovirus [Virus]

FamilyVirus-derived peptide

Tax ID11250;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Fusion inhibitor

TargetRespiratory syncytial virus (Fusion); Vero

MethodImmunoprecipitation

PaperMethods for the inhibition of respiratory syncytial virus transmission | Dani Paul Bolognesi, Thomas James Matthews, Carl T. Wild, Shawn O'Lin Barney,Dennis Michael Lambert, Stephen Robert Petteway | Trimeris, Inc., Durham NC | Patent:US6440656 Evidence URLhttps://patents.google.com/patent/US6440656/en PatentUS6440656

RECORD: Rec_0322410 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyHIV gp41 fusion inhibitor

Tax ID32630.0

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Bio-Activity Profile

Function

Antiviral Anti-HIV Anti-RSV

TargetRespiratory syncytial virus

RECORD: Rec_0326173 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0364903 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral