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MYP_119683
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Basic Information
Colicin
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibiotic activity
Enzyme / Catalytic activity ▸ Hydrolase
Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
583 amino acids
C2691H4265N813O852S10
Standard
Sequence
MSGGDGIGHNSGAHSTGGVNGSSSGRGGSSSGGGNNPNSGPGWGTTHTPDGHDIHNYNPGEFGGGGHKPGGNGGNHSGGTGDGQPPGAAMAFGFPALVPAGAGGLAVTVSGDALAAAIADVLAVLKGPFKFGAWGIALYGILPTEIAKDDPRMMSKIVTSLPADAVTESPVSSLPLDQATVSVTKRVTDVVKDERQHIAVVAGVPASIPVVDAKPTTHPGVFSVSVPGLPDLQVSTVKNAPAMTALPRGVTDEKDRTVHPAGFTFGGSSHEAVIRFPKESGQAPVYVSVTDVLTPEQVKQRQDEENRRQQEWDATHPVEVAERNYRLASDELNRANVDVAGKQERQIQAAQAVAARKGELDAANKTFADAKEEIKKFERFAHDPMAGGHRMWQMAGLKAQRAQNEVNQKQAEFNAAEKEKADADAALNVALESRKQKEQKAKDASDKLDKENKRNHPGKATGKGQPVGDKWLEDAGKEAGAPVPDRIADKLRDKEFKNFDDFRKKFWEEVSKDPELSKQFIPGNKKRMSQGLAPRARNKDTVGGRRSFELHHDKPISQDGGVYDMDNIRVTTPKLHIDIHRGK
Physicochemical Analysis
61959.24 Da
7.36
1.25
-0.09
0.0021
-0.68
0.75
-0.08
38.72
63.81
0.0515
40450.00
40450.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031483 VERIFIED: YES
Provenance & Taxonomy
Salmonella enterica [Bacterium]
Pyocin/Colicin
28901
Structure & Mods
gene-encoded linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal
Escherichia coli
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A8F6P4W9/entry
RECORD: Rec_0197654 VERIFIED: NO
Provenance & Taxonomy
Salmonella enterica subsp. enterica serovar Saintpaul [Animal]
Colicin pyosin nuclease
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic
Escherichia coli
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A1S0Z4U4/entry
RECORD: Rec_0253677 VERIFIED: NO
Provenance & Taxonomy
Salmonella muenchen [Bacterium]
Colicin/Pyocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease
Escherichia coli
PaperSKESA: strategic k-mer extension for scrupulous assemblies PMID30286803 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30286803/
RECORD: Rec_0279974 VERIFIED: YES
Provenance & Taxonomy
Salmonella [Bacterium]
Pyocin/Colicin
590
Structure & Mods
gene-encoded linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal
Escherichia coli
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A8E7VSW6/entry
RECORD: Rec_0335764 VERIFIED: NO
Provenance & Taxonomy
Salmonella enterica subsp. enterica serovar Give [Bacterium]
Colicin/Bacteriocin
28901
Structure & Mods
linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic
Escherichia coli (Gram-negative)
Qualitative functional evidence
Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30902850/
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