Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC400H601N107O103S10

DescriptionStandard

        MAPSRKTFYFAFAFFFILAQFTSGCQAGLEYAQPLPAGDFAPCEPCWLGRGKCRKMCTEDEKVVGNCKVNFFCCRRRI
    

Molecular Weight8877.36 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)4.43

Net Charge (pH 7.4) 4.08

Charge Density (pH 7.0) 0.0568

GRAVY Index0.01

Hydrophobic Moment 0.49

Boman Index0.04

Instability Index61.42

Aliphatic Index 51.41

Aromaticity 0.1667

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3358.22

LogP -28.25

H-bond Donors 124.0

H-bond Acceptors 118.0

Rotatable Bonds 283.0

Heavy Atoms 620.0

Ring Count 19.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0047381 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0194422 VERIFIED: NO