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MYP_119551
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C124H181N33O22
Standard
Sequence
AAWKWAWAKKWAKAKKWAKAA
Physicochemical Analysis
2485.97 Da
10.78
6.79
6.59
0.3233
-0.74
0.44
-0.04
-19.10
42.86
0.2381
27500.00
27500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
906.41
-1.20
34.0
29.0
79.0
179.0
10.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0200998 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
MT-1
16 μM
EC50
PaperRelative spatial positions of tryptophan and cationic residues in helical membrane-active peptides determine their cytotoxicity PMID22057278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22057278/
RECORD: Rec_0279559 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 71.4%, E 0.0%, T 14.3%, C 14.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0306966 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MT-1
16 μM
EC50
PaperPubMed PMID: 22057278 PMID22057278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22057278/
RECORD: Rec_0317987 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Tryptophan-rich synthetic anticancer peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0346292 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
HT-29
13 μM
EC50
PaperRelative spatial positions of tryptophan and cationic residues in helical membrane-active peptides determine their cytotoxicity PMID22057278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22057278/
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