Peptide Database

Peptide NameBasic phospholipase A2 homolog bothropstoxin-I (Bothropstoxin I) (BthTx-I) (BtxtxI) (svPLA2 homolog) (BOJU-I) (Myotoxic phospholipase A2-like) (Phospholipase A2 homolog 1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length137 amino acids

Chemical FormulaC680H1085N187O192S17

DescriptionStandard

        MRTLWIMAVLLVGVEGSLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTGCDPKKDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKKYRYHLKPFCKKADPC
    

Molecular Weight15497.13 Da

Isoelectric Point (pI)9.03

Net Charge (pH 7.0)10.54

Net Charge (pH 7.4) 9.96

Charge Density (pH 7.0) 0.0769

GRAVY Index-0.44

Hydrophobic Moment 0.51

Boman Index-0.09

Instability Index19.01

Aliphatic Index 68.32

Aromaticity 0.0949

Extinction Coeff. Reduced 24410.00

Extinction Coeff. Oxidized 25285.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6131.10

LogP -55.68

H-bond Donors 227.0

H-bond Acceptors 222.0

Rotatable Bonds 521.0

Heavy Atoms 1076.0

Ring Count 23.0

Amide Bonds 143.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0218427 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops jararacussu [Animal]

FamilyPhospholipase A2; Group II subfamily; K49 sub-subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Toxin Non-hemolytic

TargetNo Target Organism Found