Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC360H574N100O92S8

DescriptionStandard

        MKFHLLFFILLFWVTVLPAKKRYPEYGSLDLRKECRRSKGECRIQCLSNEIRVAFCIRPGTPCCMSSSG
    

Molecular Weight8031.54 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)6.53

Net Charge (pH 7.4) 6.16

Charge Density (pH 7.0) 0.0947

GRAVY Index0.01

Hydrophobic Moment 0.54

Boman Index-0.02

Instability Index71.98

Aliphatic Index 83.33

Aromaticity 0.1159

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3089.81

LogP -24.36

H-bond Donors 117.0

H-bond Acceptors 108.0

Rotatable Bonds 265.0

Heavy Atoms 560.0

Ring Count 14.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0366676 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence