Peptide Database

Peptide Namebeta-Defensin 2

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length42 amino acids

Chemical FormulaC190H318N60O53S6

DescriptionStandard

        TQSINNPITCLTKGGVCWGPCTGGFRQIGTCGLPRVRCCKKK
    

Molecular Weight4483.32 Da

Isoelectric Point (pI)9.61

Net Charge (pH 7.0)6.33

Net Charge (pH 7.4) 6.05

Charge Density (pH 7.0) 0.1508

GRAVY Index-0.20

Hydrophobic Moment 0.54

Boman Index-0.03

Instability Index38.65

Aliphatic Index 60.24

Aromaticity 0.0476

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1829.36

LogP -23.21

H-bond Donors 70.0

H-bond Acceptors 66.0

Rotatable Bonds 146.0

Heavy Atoms 309.0

Ring Count 6.0

Amide Bonds 45.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0176954 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide10-38; 17-31; 21-39

Bio-Activity Profile

Function

Antimicrobial