Peptide Database

Peptide NameChimeric CNP-D

Function Ontology

Natriuretic

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC176H305N55O49S2

DescriptionStandard

        GLSKGFGLKLDRISMSGLGCVQQRKESKKPPAKLQPR
    

Molecular Weight4039.77 Da

Isoelectric Point (pI)10.65

Net Charge (pH 7.0)6.75

Net Charge (pH 7.4) 6.52

Charge Density (pH 7.0) 0.1824

GRAVY Index-0.75

Hydrophobic Moment 0.47

Boman Index-0.22

Instability Index39.11

Aliphatic Index 73.78

Aromaticity 0.0270

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1711.16

LogP -18.93

H-bond Donors 60.0

H-bond Acceptors 58.0

Rotatable Bonds 143.0

Heavy Atoms 282.0

Ring Count 4.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0235417 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyNatriuretic peptide

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide6-22

Bio-Activity Profile

Function

Natriuretic

MethodCompetitive Radioimmunoassay

Half-LifeRat plasma (Intravenous), in vivo; 1218 s