Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC477H775N125O137S7

DescriptionStandard

        MKLFLVLIILLFEVPKDAAQHRRCFSSISGYCRKKCKLGETYEIACVNGKLCCINEDEKRQYQQAIEPPAPSRKPDLELDYAILPTVTLSTISL
    

Molecular Weight10677.47 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)1.54

Net Charge (pH 7.4) 1.15

Charge Density (pH 7.0) 0.0164

GRAVY Index-0.06

Hydrophobic Moment 0.57

Boman Index0.01

Instability Index50.23

Aliphatic Index 101.70

Aromaticity 0.0745

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4215.28

LogP -34.51

H-bond Donors 150.0

H-bond Acceptors 147.0

Rotatable Bonds 357.0

Heavy Atoms 746.0

Ring Count 14.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0046926 VERIFIED: NO

Provenance & Taxonomy

OrganismNeophocaena asiaeorientalis asiaeorientalis [Bacterium]

FamilyDefensin

Tax ID1706337

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence