Peptide Database

Peptide NameColicin pyocin immunity family protein (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length159 amino acids

Chemical FormulaC824H1252N230O234S

DescriptionStandard

        MSPQPGSAPVFPQHTGTDIRFLATKRTLTFLAHEEVSFHDYIIWFPAESGLEPVYVYFNKPRKGVVDAGHDYHPAPKIEDITGFLNLNKSKRKTPKQGGSGKRERWIDQKGRKIYEWDSQHGELEGYRASDGQHLGAFNYKTGVQLKPADPNRDIKKYL
    

Molecular Weight18156.22 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)5.12

Net Charge (pH 7.4) 4.50

Charge Density (pH 7.0) 0.0322

GRAVY Index-0.86

Hydrophobic Moment 0.76

Boman Index-0.11

Instability Index41.83

Aliphatic Index 62.58

Aromaticity 0.1195

Extinction Coeff. Reduced 28420.00

Extinction Coeff. Oxidized 28420.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7462.47

LogP -69.59

H-bond Donors 255.0

H-bond Acceptors 247.0

Rotatable Bonds 593.0

Heavy Atoms 1289.0

Ring Count 41.0

Amide Bonds 170.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0096992 VERIFIED: YES

Provenance & Taxonomy

OrganismYersinia enterocolitica subsp. enterocolitica [Bacterium]

FamilyPyocin/Colicin

Tax ID150052

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli

RECORD: Rec_0360137 VERIFIED: YES

Provenance & Taxonomy

OrganismYersinia enterocolitica [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)