Peptide Database

Peptide NameSLAY-screened peptide P3320

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC85H140N24O35S2

DescriptionStandard

        SNSIGKLSAVDSSCSYCISSN
    

Molecular Weight2122.29 Da

Isoelectric Point (pI)5.55

Net Charge (pH 7.0)-0.56

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0267

GRAVY Index0.06

Hydrophobic Moment 0.23

Boman Index0.07

Instability Index37.32

Aliphatic Index 74.29

Aromaticity 0.0476

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 976.89

LogP -17.36

H-bond Donors 37.0

H-bond Acceptors 37.0

Rotatable Bonds 70.0

Heavy Atoms 146.0

Ring Count 1.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0006582 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/