Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length120 amino acids

Chemical FormulaC548H870N164O171S10

DescriptionStandard

        MRTLALLAALLLLALQAQAEPLPENNEEAPDQEQPGEEDQDMAISFAGPEAPGLQRSGPSLGHPGVCPQCPIHVSVSVSPGLPRNPPCSCRRGGCSLSERFSGSCFQDGKRYPLCCRRGW
    

Molecular Weight12812.42 Da

Isoelectric Point (pI)5.29

Net Charge (pH 7.0)-3.38

Net Charge (pH 7.4) -3.83

Charge Density (pH 7.0) -0.0281

GRAVY Index-0.38

Hydrophobic Moment 0.60

Boman Index-0.02

Instability Index75.15

Aliphatic Index 70.00

Aromaticity 0.0417

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5272.52

LogP -62.68

H-bond Donors 182.0

H-bond Acceptors 180.0

Rotatable Bonds 405.0

Heavy Atoms 893.0

Ring Count 23.0

Amide Bonds 130.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0347033 VERIFIED: NO

Provenance & Taxonomy

OrganismMarmota marmota marmota [Animal]

FamilyDefensin

Tax ID9994

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal