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MYP_119235
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Basic Information
Pumilarin (46-70)[G2W,T5K,Q8K,Y9K,G18W], Syn-Safencin-P96
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
25 amino acids
C151H252N44O31
Standard
Sequence
AWKEKIRKKLKNEIKKKWRKAVIAW
Physicochemical Analysis
3179.89 Da
10.84
8.79
8.59
0.3517
-1.22
0.68
-0.41
3.72
86.00
0.1200
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1284.76
-4.60
47.0
40.0
116.0
226.0
6.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0310720 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas syringae
PMID29463889;32566907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29463889/
RECORD: Rec_0337177 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii NCTC 13424
2 μg/mL
MIC
PMID29463889;32566907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29463889/
RECORD: Rec_0360245 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa PAO1
16 μg/mL
MIC
PMID29463889;32566907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29463889/
RECORD: Rec_0393252 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
Human keratinocytes HaCat
10 μM
Cytotoxicity
PMID29463889;32566907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29463889/
RECORD: Rec_0411962 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis NCTC 775
128 μg/mL
MIC
PMID29463889;32566907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29463889/
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