Peptide Database

Peptide NameBeta-defensin 110 (Beta-defensin 10) (DEFB-10) (Beta-defensin 11) (DEFB-11) (Beta-defensin 111) (Defensin; beta 110) (Defensin; beta 111)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC359H560N102O92S7

DescriptionStandard

        MKIQLFFFILHFWVTILPAKKKYPEYGSLDLRRECRIGNGQCKNQCHENEIRIAYCIRPGTHCCLQQ
    

Molecular Weight8001.37 Da

Isoelectric Point (pI)9.06

Net Charge (pH 7.0)4.71

Net Charge (pH 7.4) 4.23

Charge Density (pH 7.0) 0.0703

GRAVY Index-0.30

Hydrophobic Moment 0.56

Boman Index-0.04

Instability Index50.23

Aliphatic Index 82.99

Aromaticity 0.1194

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3151.58

LogP -23.89

H-bond Donors 114.0

H-bond Acceptors 107.0

Rotatable Bonds 266.0

Heavy Atoms 560.0

Ring Count 15.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0407694 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyBeta-defensin; Defensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic