Peptide Database

Peptide NameSLAY-screened peptide P5742

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC111H168N28O28S

DescriptionStandard

        EDNCLKRLYIPLHIVHFYT
    

Molecular Weight2374.76 Da

Isoelectric Point (pI)7.00

Net Charge (pH 7.0)-0.00

Net Charge (pH 7.4) -0.29

Charge Density (pH 7.0) -0.0000

GRAVY Index-0.02

Hydrophobic Moment 0.48

Boman Index0.10

Instability Index65.30

Aliphatic Index 117.89

Aromaticity 0.1579

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 901.99

LogP -3.49

H-bond Donors 32.0

H-bond Acceptors 31.0

Rotatable Bonds 74.0

Heavy Atoms 168.0

Ring Count 6.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0330398 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/