Peptide Database

Peptide NameCycloviolacin O7

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC126H197N31O37S6

DescriptionStandard

        SFPCGESCVFIPCISAIAGCSCKNKVCY
    

Molecular Weight2930.49 Da

Isoelectric Point (pI)7.52

Net Charge (pH 7.0)0.40

Net Charge (pH 7.4) 0.10

Charge Density (pH 7.0) 0.0143

GRAVY Index0.81

Hydrophobic Moment 0.28

Boman Index0.28

Instability Index40.31

Aliphatic Index 69.64

Aromaticity 0.1071

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1065.02

LogP -11.77

H-bond Donors 42.0

H-bond Acceptors 44.0

Rotatable Bonds 90.0

Heavy Atoms 200.0

Ring Count 5.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0278931 VERIFIED: YES

Provenance & Taxonomy

OrganismGloeospermum blakeanum [Plant]

FamilyCyclotide

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)