Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC211H334N58O75S5

DescriptionStandard

        MANNKKDQFDLDVQVNKAKGDVEPQITSVSLCTPGCGETGSFNSYCC
    

Molecular Weight5043.58 Da

Isoelectric Point (pI)4.53

Net Charge (pH 7.0)-2.53

Net Charge (pH 7.4) -2.82

Charge Density (pH 7.0) -0.0539

GRAVY Index-0.48

Hydrophobic Moment 0.27

Boman Index-0.04

Instability Index31.82

Aliphatic Index 53.83

Aromaticity 0.0638

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2175.69

LogP -29.50

H-bond Donors 75.0

H-bond Acceptors 78.0

Rotatable Bonds 168.0

Heavy Atoms 349.0

Ring Count 5.0

Amide Bonds 53.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0023672 VERIFIED: NO

Provenance & Taxonomy

OrganismMarininema mesophilum [other]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria