Peptide Database

Peptide NameAntimicrobial peptide ToAp1

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC390H627N103O100S4

DescriptionStandard

        MQMKYLIPIFFLVLIVADHCHAFIGMIPGLIGGLISAFKGRRKRDITAQIEQYRNIQKREAAELEELLANLPVY
    

Molecular Weight8487.04 Da

Isoelectric Point (pI)8.93

Net Charge (pH 7.0)1.67

Net Charge (pH 7.4) 1.32

Charge Density (pH 7.0) 0.0226

GRAVY Index0.29

Hydrophobic Moment 0.49

Boman Index0.15

Instability Index46.65

Aliphatic Index 121.35

Aromaticity 0.0946

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3252.98

LogP -18.32

H-bond Donors 112.0

H-bond Acceptors 108.0

Rotatable Bonds 286.0

Heavy Atoms 597.0

Ring Count 12.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0071810 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus obscurus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Antibiofilm Anti-Candida Anti-Gram-positive Anti-inflammatory Cytotoxic Hemolytic

TargetMycobacterium abscessus

RECORD: Rec_0330584 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus obscurus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Antibiofilm Anti-Candida Anti-Gram-positive Anti-inflammatory Cytotoxic Hemolytic

TargetCandida spp.

RECORD: Rec_0387288 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus obscurus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Antibiofilm Anti-Candida Anti-Gram-positive Anti-inflammatory Cytotoxic Hemolytic

TargetCryptococcus neoformans

RECORD: Rec_0422248 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus obscurus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Antibiofilm Anti-Candida Anti-Gram-positive Anti-inflammatory Cytotoxic Hemolytic

TargetCandida albicans