Peptide Database

Peptide NameSLAY-screened peptide P1568

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC123H177N37O28S

DescriptionStandard

        RYLSSFWRSLARFWKRYNNC
    

Molecular Weight2654.02 Da

Isoelectric Point (pI)10.94

Net Charge (pH 7.0)4.75

Net Charge (pH 7.4) 4.53

Charge Density (pH 7.0) 0.2374

GRAVY Index-0.91

Hydrophobic Moment 0.98

Boman Index-0.31

Instability Index48.42

Aliphatic Index 44.00

Aromaticity 0.3000

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1108.75

LogP -8.61

H-bond Donors 44.0

H-bond Acceptors 34.0

Rotatable Bonds 83.0

Heavy Atoms 189.0

Ring Count 8.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0046487 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/