Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length125 amino acids

Chemical FormulaC619H1030N174O178S7

DescriptionStandard

        FLVVKKCLKGFGKCRDSCLVGETEVKDCKSKKCCIGPKVIELIKSYLRHEIPHIPDNDLVEMLKNEKKSREGVERKHTLGPLSQIQDANSLLNITSAIVPNASPLKLYASRLTRKPVPALYATEH
    

Molecular Weight13982.31 Da

Isoelectric Point (pI)9.28

Net Charge (pH 7.0)8.06

Net Charge (pH 7.4) 7.52

Charge Density (pH 7.0) 0.0645

GRAVY Index-0.33

Hydrophobic Moment 0.75

Boman Index-0.08

Instability Index44.30

Aliphatic Index 97.44

Aromaticity 0.0400

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5671.58

LogP -52.50

H-bond Donors 200.0

H-bond Acceptors 197.0

Rotatable Bonds 478.0

Heavy Atoms 978.0

Ring Count 17.0

Amide Bonds 131.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0139558 VERIFIED: NO

Provenance & Taxonomy

OrganismNeotoma lepida [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal