Peptide Database

Peptide NameLeukemia inhibitory factor

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length180 amino acids

Chemical FormulaC881H1415N247O255S10

DescriptionStandard

        SPLPITPVNATCAIRHPCHGNLMNQIKNQLAQLNGSANALFISYYTAQGEPFPNNVEKLCAPNMTDFPSFHGNGTEKTKLVELYRMVAYLSASLTNITRDQKVLNPTAVSLQVKLNATIDVMRGLLSNVLCRLCNKYRVGHVDVPPVPDHSDKEAFQRKKLGCQLLGTYKQVISVVVQAF
    

Molecular Weight19867.81 Da

Isoelectric Point (pI)9.20

Net Charge (pH 7.0)6.84

Net Charge (pH 7.4) 6.25

Charge Density (pH 7.0) 0.0380

GRAVY Index-0.12

Hydrophobic Moment 0.62

Boman Index0.05

Instability Index18.94

Aliphatic Index 93.11

Aromaticity 0.0667

Extinction Coeff. Reduced 8940.00

Extinction Coeff. Oxidized 9315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8063.42

LogP -95.32

H-bond Donors 275.0

H-bond Acceptors 277.0

Rotatable Bonds 650.0

Heavy Atoms 1393.0

Ring Count 29.0

Amide Bonds 204.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0384411 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyLIF/OSM family

Tax ID10090; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-134; 18-131; 60-163

Bio-Activity Profile

Function

Cytokine Growth factor LIF OSM family Growth factor signaling Angiogenic