Peptide Database

Peptide NameSLAY-screened peptide P1090

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC76H116N24O18

DescriptionStandard

        QYYVLHRRRLSY
    

Molecular Weight1653.88 Da

Isoelectric Point (pI)10.27

Net Charge (pH 7.0)2.84

Net Charge (pH 7.4) 2.59

Charge Density (pH 7.0) 0.2370

GRAVY Index-1.09

Hydrophobic Moment 0.20

Boman Index-0.42

Instability Index108.63

Aliphatic Index 89.17

Aromaticity 0.2500

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 721.81

LogP -4.66

H-bond Donors 28.0

H-bond Acceptors 22.0

Rotatable Bonds 52.0

Heavy Atoms 118.0

Ring Count 4.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0079502 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/