Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length498 amino acids

Chemical FormulaC2539H3910N634O720S16

DescriptionStandard

        MHTKMVQVLWGYFLLWNFYFSSAHTIYPGIKARATQRALDYGVQAGIEMIEQMAKERNIPDLKGSESLEFLKIDYVNYNFSNIKINAFSFPNTSLAFVPGVGIKALTNHGTANISTHWDVKSPLFQDTGGADLFLSGVYFTGILILARNDFGHPILKLQDCYAQVSHAHVSFSGELSVLYNSFAEPMEKPILKNLNEMLCPIITGEVEALNANLSMLEGESRNRLFGEVLFPPANSSAPQGVFYPLENLTDPPFPPVPFMLPERSDSMLYVGISEYFFKSASFAYFTAGAFNVTLSTKEISSHLVQNSQGIGNVLSRIAEIYILSQPFMIRIMATEPPVINLLPGNFTLDIPASIMILTQPENSTIEPIVSMDFVASTSVGLVILGQRLICSLSLNRFRLTLPESSRSNIEVLKFENILSFIIHFGILPLANAKLQQGFPLPNPHKISFVNSDIEVLEHFLLISTDLKYETSLKQQPSFHGWEGLNLISGQWSGKSAP
    

Molecular Weight55349.06 Da

Isoelectric Point (pI)5.58

Net Charge (pH 7.0)-10.42

Net Charge (pH 7.4) -11.40

Charge Density (pH 7.0) -0.0209

GRAVY Index0.13

Hydrophobic Moment 0.67

Boman Index0.19

Instability Index43.91

Aliphatic Index 99.28

Aromaticity 0.1104

Extinction Coeff. Reduced 49850.00

Extinction Coeff. Oxidized 49975.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0168445 VERIFIED: NO

Provenance & Taxonomy

OrganismPteropus vampyrus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria