Peptide Database

Peptide NamevCXCL1

Function Ontology

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC495H772N154O129S4

DescriptionStandard

        TELRCCRLHRKWPPNKIILGNYWLHRDPRGPGCDKNEHLLYPDGRKPPGPGVCLSPDHLFSKWLDKHNDNRWYNVNITKSPGPRRINITLIGVRG
    

Molecular Weight11072.64 Da

Isoelectric Point (pI)9.89

Net Charge (pH 7.0)8.80

Net Charge (pH 7.4) 8.27

Charge Density (pH 7.0) 0.0926

GRAVY Index-0.92

Hydrophobic Moment 0.63

Boman Index-0.18

Instability Index52.31

Aliphatic Index 74.84

Aromaticity 0.0842

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4534.92

LogP -41.31

H-bond Donors 160.0

H-bond Acceptors 147.0

Rotatable Bonds 351.0

Heavy Atoms 782.0

Ring Count 28.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0017153 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Chemotactic Immunomodulatory Signaling peptide

TargetCXCR1 (Human); CXCR2 (Human)

Activity44 nM

MethodIC50