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MYP_118834
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Basic Information
Bim SM-5
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C63H103N19O20
Standard
Sequence
IAQELRRIGDEF
Physicochemical Analysis
1446.61 Da
4.68
-1.23
-1.44
-0.1028
-0.50
0.78
-0.18
89.00
105.83
0.0833
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
662.21
-5.24
23.0
19.0
50.0
102.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0183941 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Pal, CH3(CH2)14CO
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
U-937 (45% Killing= 50 μM)
RECORD: Rec_0185025 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
RECORD: Rec_0186031 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugated small molecule: Palmitic acid
Bio-Activity Profile
Anticancer Cytotoxic
HepG2
1.20 μM
IC50
PaperBioorganic and Medicinal Chemistry Letters. 2019 PMID30501963 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30501963/
RECORD: Rec_0213553 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
U-937 (45% Killing= 50 μM)
RECORD: Rec_0219906 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HL-60 (23% Killing= 50 μM)
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