‹ ›
MYP_118808
← PREVIOUS NEXT → BACK
Basic Information
buCATHL4B
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C91H138N24O15
Standard
Sequence
AIPWIWIWRLLRKG
Physicochemical Analysis
1808.22 Da
12.00
2.79
2.61
0.1996
0.38
0.65
0.24
12.86
146.43
0.2143
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
630.02
1.92
24.0
18.0
54.0
130.0
7.0
13.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0074686 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Listeria monocytogenes ATCC-19111
12.5 μM
MIC
PaperDiversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins.
RECORD: Rec_0076438 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
A. johnsonii NCDC-0072
12.5 μM
MIC
PaperDiversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins.
RECORD: Rec_0079148 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
89462
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Buffalo erythrocytes (55% Hemolysis at 150 microM, Human erythrocytes (100% Hemolysis at 15 microM, Sheep erythrocytes (15% Hemolysis at 7.5 microM
150 μM
Hemolysis
PMID26675301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26675301/
RECORD: Rec_0080830 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0083012 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
89462
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter johnsonii NCDC 0072
12.5 μM
MIC
PMID26675301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26675301/
1 2 3 ... 7 NEXT LAST
Showing 5 records on this page · Page 1 of 7