Peptide Database

Peptide Namepegozafermin

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length181 amino acids

Chemical FormulaC863H1342N238O262S3

DescriptionStandard

        HPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAHLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPALPEPPGILAPQPPDVGSSDPLSMVGPTQGASPSYAS
    

Molecular Weight19339.52 Da

Isoelectric Point (pI)5.24

Net Charge (pH 7.0)-6.71

Net Charge (pH 7.4) -7.28

Charge Density (pH 7.0) -0.0371

GRAVY Index-0.43

Hydrophobic Moment 0.65

Boman Index0.04

Instability Index58.55

Aliphatic Index 81.44

Aromaticity 0.0608

Extinction Coeff. Reduced 8940.00

Extinction Coeff. Oxidized 9065.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7781.28

LogP -88.93

H-bond Donors 255.0

H-bond Acceptors 264.0

Rotatable Bonds 600.0

Heavy Atoms 1366.0

Ring Count 43.0

Amide Bonds 194.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0206066 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Immunomodulatory Signaling peptide

Targetfibroblast growth factor receptor 1 (Human)

Activity0.6 nM

MethodEC50