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MYP_118733
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Basic Information
D0-NH2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
10 amino acids
C47H91N19O12S2
Standard
Sequence
SGKLCCRRKK
Physicochemical Analysis
1178.48 Da
10.33
4.44
4.20
0.4437
-1.31
0.27
-0.76
49.30
39.00
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
547.31
-6.80
23.0
19.0
44.0
80.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0289928 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (3% Hemolysis at 100 microM, Human erythrocytes (2% Hemolysis at 100 microM
100 μM
Hemolysis
PMID23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23860860/
RECORD: Rec_0315237 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PaperPubMed PMID: 22518150 | PubMed PMID: 23860860 PMID22518150;23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22518150/
RECORD: Rec_0339170 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli
12 μM
MIC
PaperDesign of short membrane selective antimicrobial peptides containing tryptophan and arginine residues for improved activity, salt-resistance, and biocompatibility.
RECORD: Rec_0343633 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
100 μM
MIC
PMID23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23860860/
RECORD: Rec_0367668 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperPubMed PMID: 22518150 | PubMed PMID: 23860860 PMID22518150;23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22518150/
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