Peptide Database

Peptide NameDefensin 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC349H584N104O99S11

DescriptionStandard

        MEKKALSLLFMLFLLLASDVSVKRADALLGRCKVKSSRYTGACLTDTKCSTVCRGEGYKGGDCHGFRRRCMCLC
    

Molecular Weight8173.72 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)7.51

Net Charge (pH 7.4) 7.11

Charge Density (pH 7.0) 0.1015

GRAVY Index0.08

Hydrophobic Moment 0.59

Boman Index-0.06

Instability Index41.15

Aliphatic Index 80.41

Aromaticity 0.0676

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3298.30

LogP -34.42

H-bond Donors 130.0

H-bond Acceptors 119.0

Rotatable Bonds 282.0

Heavy Atoms 563.0

Ring Count 6.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0307293 VERIFIED: NO

Provenance & Taxonomy

OrganismLens ervoides [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal