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MYP_118719
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Basic Information
Rufomycin-1, Rufomycin B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
7 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XXXAXLX
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0258707 VERIFIED: YES
Provenance & Taxonomy
Streptomyces atratus MJM3502 [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 1,2,3,5,7
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium tuberculosis H37Rv
0.02 μM
MIC
PMID30602512 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30602512/
RECORD: Rec_0294897 VERIFIED: YES
Provenance & Taxonomy
Bacteria [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID30602512 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30602512/
RECORD: Rec_0308029 VERIFIED: YES
Provenance & Taxonomy
Bacteria [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID30602512 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30602512/
RECORD: Rec_0329350 VERIFIED: YES
Provenance & Taxonomy
Streptomyces atratus MJM3502 [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 1,2,3,5,7
Bio-Activity Profile
Hemolytic
Vero cells (IC50 at >50 μM
50 μM
Hemolysis
PMID30602512 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30602512/
RECORD: Rec_0403274 VERIFIED: YES
Provenance & Taxonomy
Bacteria [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID30602512 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30602512/