Peptide Database

Peptide NameHepcidin antimicrobial peptide (Latescidin 1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC424H676N120O122S14

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAIPFPGVQELEEAGSNDTPVAAHQEMSMESWMMPNHIRQKRQSHLSLCRVCCNCCKNKGCGFCCRF
    

Molecular Weight9855.54 Da

Isoelectric Point (pI)7.54

Net Charge (pH 7.0)0.69

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0077

GRAVY Index0.21

Hydrophobic Moment 0.58

Boman Index0.10

Instability Index60.57

Aliphatic Index 76.74

Aromaticity 0.0674

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3850.59

LogP -39.32

H-bond Donors 140.0

H-bond Acceptors 140.0

Rotatable Bonds 325.0

Heavy Atoms 680.0

Ring Count 14.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0244632 VERIFIED: NO

Provenance & Taxonomy

OrganismLates calcarifer [Animal]

FamilyHepcidin

Tax ID8187

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal