Peptide Database

Peptide NameNeurotensin

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC69H119N21O17

DescriptionStandard

        QAIVSKARRPYIL
    

Molecular Weight1514.81 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.2122

GRAVY Index0.04

Hydrophobic Moment 0.53

Boman Index-0.08

Instability Index76.39

Aliphatic Index 127.69

Aromaticity 0.0769

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 637.10

LogP -4.58

H-bond Donors 23.0

H-bond Acceptors 20.0

Rotatable Bonds 49.0

Heavy Atoms 107.0

Ring Count 2.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0237386 VERIFIED: YES

Provenance & Taxonomy

OrganismRhinella marina [Animal]

FamilyNeurotensin

Tax ID8386

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Bio-Activity Profile

Function

ACE inhibitory

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour