Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length160 amino acids

Chemical FormulaC771H1203N221O228S3

DescriptionStandard

        MAVVSEKTAGGRNVLAFLDMLAWSEGTSTIRGSDNGYNVVVGGGLFNGYADHPRLKVYLPRYKVYSTAAGRYQLLSRYWDAYRESLALKGGFTPANQDLVALQQIKERRALADIQAGRLADAVQKCSNIWASLPGAGYGQREHSLDDLAAHYLAAGGVLS
    

Molecular Weight17312.34 Da

Isoelectric Point (pI)9.01

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.34

Charge Density (pH 7.0) 0.0173

GRAVY Index-0.17

Hydrophobic Moment 0.64

Boman Index0.05

Instability Index20.26

Aliphatic Index 89.75

Aromaticity 0.1000

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 31400.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7233.84

LogP -74.50

H-bond Donors 256.0

H-bond Acceptors 237.0

Rotatable Bonds 567.0

Heavy Atoms 1223.0

Ring Count 26.0

Amide Bonds 172.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038070 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudomonas phage D3 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic

RECORD: Rec_0131211 VERIFIED: NO

Provenance & Taxonomy

OrganismDetrevirus PMG1 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic

RECORD: Rec_0307021 VERIFIED: NO

Provenance & Taxonomy

OrganismPseudomonas aeruginosa [Bacterium]

FamilyGlycosyl hydrolase 24

Tax ID287

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic Non-ribosomal

MethodQualitative functional evidence