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MYP_118696
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Basic Information
Brevinin-2TEa (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
29 amino acids
C125H224N36O36S4
Standard
Sequence
GIGSMLLGLAKNVGMSLLNKAQCKISGKC
Physicochemical Analysis
2935.60 Da
9.70
3.74
3.50
0.1288
0.49
0.41
0.20
18.66
111.03
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1172.16
-12.98
42.0
44.0
106.0
201.0
0.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0093040 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa (ATCC 10145)
100 μg/mL
MIC
PMID21412958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21412958/
RECORD: Rec_0165929 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0169829 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]; Indosylvirana temporalis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic Anti-Gram-negative
Escherichia coli
0.04 μg/mL
MIC
RECORD: Rec_0265364 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
23-29
Bio-Activity Profile
Antimicrobial Antibacterial
Evidence URLhttps://www.uniprot.org/uniprotkb/D6N2U0/entry
RECORD: Rec_0399376 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (ATCC25923)
150 μg/mL
MIC
PMID21412958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21412958/
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