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MYP_118696
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Basic Information
Brevinin-2TEa (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
29 amino acids
C125H224N36O36S4
Standard
Sequence
GIGSMLLGLAKNVGMSLLNKAQCKISGKC
Physicochemical Analysis
2935.60 Da
9.70
3.74
3.50
0.1288
0.49
0.41
0.20
18.66
111.03
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1172.16
-12.98
42.0
44.0
106.0
201.0
0.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012161 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus cereus (NCLM 2156)
150 μg/mL
MIC
PMID21412958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21412958/
RECORD: Rec_0030252 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPatent WO 2019/077634 A2 Evidence URLhttps://patents.google.com/patent/WO2019077634A2/en PatentWO 2019/077634 A2
RECORD: Rec_0030281 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]; Indosylvirana temporalis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic
Haemolytic activity against human red blood cells
49.7 μg/mL
MIC
RECORD: Rec_0031830 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
cholerae (PL 91)
150 μg/mL
MIC
PMID21412958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21412958/
RECORD: Rec_0060668 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli (NCLM 2064)
40 μg/mL
MIC
PMID21412958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21412958/
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