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MYP_118694
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Basic Information
TAT-RasGAP317326
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
22 amino acids
C119H201N49O29S
Standard
Sequence
GRKKRRQRRRGGWMWVTNLRTD
Physicochemical Analysis
2814.25 Da
12.00
7.76
7.55
0.3528
-2.01
0.51
-0.80
123.55
30.91
0.0909
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1355.28
-15.15
53.0
38.0
98.0
198.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0259344 VERIFIED: YES
Provenance & Taxonomy
RasGAP-derived peptides [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7 (rendered all the tested cancer cell lines sensitive to doses of cisplatin, adriamycin, and mitoxantrone )
PaperPubMed PMID: 15467750 PMID15467750 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15467750/
RECORD: Rec_0282154 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 18.2%, E 18.2%, T 36.4%, C 27.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0283588 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa 547
75 μg/mL
IC50
PMID28638371;27602963 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28638371/
RECORD: Rec_0293769 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID15467750 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15467750/
RECORD: Rec_0297599 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa
128 μg/mL
MIC
PMID28638371;27602963 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28638371/
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