MYP_118694
Basic Information
TAT-RasGAP317326
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antifungal
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Standard
22 amino acids
C119H201N49O29S
Standard
Sequence
GRKKRRQRRRGGWMWVTNLRTD
Physicochemical Analysis
2814.25 Da
12.00
7.76
7.55
0.3528
-2.01
0.51
-0.80
123.55
30.91
0.0909
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1355.28
-15.15
53.0
38.0
98.0
198.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000732 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Streptococcus pneumoniae ATCC 49619
30 μg/mL
IC50
RECORD: Rec_0009428 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Acinetobacter baumannii ATCC 19606
8 μg/mL
MIC
RECORD: Rec_0013014 VERIFIED: YES
Provenance & Taxonomy
RasGAP-derived peptides [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HeLa (rendered all the tested cancer cell lines sensitive to doses of cisplatin, adriamycin, and mitoxantrone )
RECORD: Rec_0016891 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Burkholderia cepacia ATCC 25416
256 μg/mL
MIC
RECORD: Rec_0027057 VERIFIED: YES
Provenance & Taxonomy
RasGAP-derived peptides [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
U2OS (rendered all the tested cancer cell lines sensitive to doses of cisplatin, adriamycin, and mitoxantrone )
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