Peptide Database

Peptide Namesynthetic peptide from alpha-gliadin

Function Ontology

Venom / Toxin ▸ General toxin ▸ Celiac toxic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC64H104N16O22

DescriptionStandard

        VLQQSTYQLLQE
    

Molecular Weight1449.60 Da

Isoelectric Point (pI)4.60

Net Charge (pH 7.0)-1.26

Net Charge (pH 7.4) -1.48

Charge Density (pH 7.0) -0.1049

GRAVY Index-0.39

Hydrophobic Moment 0.40

Boman Index0.01

Instability Index132.22

Aliphatic Index 121.67

Aromaticity 0.0833

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 653.77

LogP -6.23

H-bond Donors 21.0

H-bond Acceptors 21.0

Rotatable Bonds 49.0

Heavy Atoms 102.0

Ring Count 1.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0064004 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin-derived

Tax ID4565;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Celiac toxic

Targetgliadin-reactive enterocyte / calreticulin cross-reactivity assays

PaperKrupickova S., Tuckova L., Flegelove Z., Michalak M., Walters J. R. F., Whelan A., Harries J., Vencovsky J., Tlaskalova-Hogenova H.. Identification of common epitopes on gliadin, enterocytes, and calreticulin recognised antigliadin antibodies of patients with coeliac disease. Gut, 1999, 44, 168-173. PMID9895374 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9895374/

RECORD: Rec_0303754 VERIFIED: YES