Peptide Database

Peptide NameDermaseptin-SP3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC117H193N35O36S

DescriptionStandard

        SLWSSIKDMAAAAGRAALNAVNGIVNP
    

Molecular Weight2698.06 Da

Isoelectric Point (pI)8.46

Net Charge (pH 7.0)0.46

Net Charge (pH 7.4) 0.25

Charge Density (pH 7.0) 0.0170

GRAVY Index0.42

Hydrophobic Moment 0.59

Boman Index0.23

Instability Index14.04

Aliphatic Index 105.19

Aromaticity 0.0370

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1142.10

LogP -13.64

H-bond Donors 39.0

H-bond Acceptors 38.0

Rotatable Bonds 86.0

Heavy Atoms 189.0

Ring Count 3.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0042998 VERIFIED: YES

Provenance & Taxonomy

OrganismThe gliding tree [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

TargetEscherichia coli ATCC 25922

Activity47 μM

MethodMIC

RECORD: Rec_0050821 VERIFIED: YES

Provenance & Taxonomy

OrganismAgalychnis spurrelli [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli ATCC 25922

Activity128 μg/mL

MethodMIC

RECORD: Rec_0157709 VERIFIED: YES

Provenance & Taxonomy

OrganismAgalychnis spurrelli [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetCandida albicans

Activity512 μg/mL

MethodMIC

RECORD: Rec_0316513 VERIFIED: YES

Provenance & Taxonomy

OrganismAgalychnis spurrelli [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC 25923

Activity512 μg/mL

MethodMIC