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MYP_118580
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Basic Information
Bacteriocin L-1077
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
37 amino acids
C185H290N48O49S
Standard
Sequence
TNYGNGVGVPDAIMAGIIKLIFIFNIRQGYNFGKKAT
Physicochemical Analysis
4002.64 Da
9.82
2.39
2.20
0.0647
0.26
0.72
0.25
2.77
97.57
0.1351
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1575.76
-13.13
53.0
53.0
132.0
283.0
6.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0044442 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Shigella dysenteriae
0.76 μg/mL
MIC
PMID21378051 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21378051/
RECORD: Rec_0046964 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0053516 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enteritidis 237
0.19 μg/mL
MIC
PMID21378051 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21378051/
RECORD: Rec_0062466 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus Salivarius 1077 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli O157:H7 G-35
0.19 μg/mL
MIC
PMID21378051 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21378051/
RECORD: Rec_0065695 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
P. vulgaris
1.5 μg/mL
MIC
PaperIsolation of Lactobacillus salivarius 1077 (NRRL B-50053) and characterization of its bacteriocin, including the antimicrobial activity spectrum.
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