Peptide Database

Peptide NameChicken LEAP-2

Function Ontology

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Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC194H326N62O56S5

DescriptionStandard

        MTPFWRGVSLRPIGASCRDDSECITKLCRKRRCSLIVAQE
    

Molecular Weight4583.37 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)3.47

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.0868

GRAVY Index-0.26

Hydrophobic Moment 0.56

Boman Index-0.19

Instability Index71.03

Aliphatic Index 78.00

Aromaticity 0.0500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1933.54

LogP -20.84

H-bond Donors 75.0

H-bond Acceptors 65.0

Rotatable Bonds 153.0

Heavy Atoms 317.0

Ring Count 5.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0180460 VERIFIED: YES

Provenance & Taxonomy

OrganismCastor canadensis [Animal]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)