Peptide Database

Peptide NameRugosin-RN antimicrobial peptide (Fragment)

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC340H565N87O114S4

DescriptionStandard

        KKSLLLLFLLGTISLSLCEEERGADEDDGEEMTEEEVKRSFLSKFKDIALDVAKNAGKGVLTTLACKIDGSC
    

Molecular Weight7823.90 Da

Isoelectric Point (pI)4.62

Net Charge (pH 7.0)-5.25

Net Charge (pH 7.4) -5.52

Charge Density (pH 7.0) -0.0729

GRAVY Index-0.11

Hydrophobic Moment 0.65

Boman Index-0.00

Instability Index46.92

Aliphatic Index 100.28

Aromaticity 0.0417

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3266.27

LogP -31.82

H-bond Donors 116.0

H-bond Acceptors 113.0

Rotatable Bonds 279.0

Heavy Atoms 545.0

Ring Count 3.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0052590 VERIFIED: NO

Provenance & Taxonomy

OrganismRana nigrovittata [Animal]

FamilyRugosin

Tax ID127021

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0321381 VERIFIED: NO

Provenance & Taxonomy

OrganismSylvirana [Animal]

Tax ID1659747

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal