Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC508H829N135O141S9

DescriptionStandard

        MGLFMIIAILLFQKPTVTEQLKKCWNNYVQRHCRKICRVNEVPEALCENGRYCCLNIKELEACKKITKPPSPKPATLALTLQDYVTIIENFPSLKTQST
    

Molecular Weight11372.42 Da

Isoelectric Point (pI)9.05

Net Charge (pH 7.0)5.53

Net Charge (pH 7.4) 5.13

Charge Density (pH 7.0) 0.0558

GRAVY Index-0.14

Hydrophobic Moment 0.95

Boman Index0.00

Instability Index51.28

Aliphatic Index 94.55

Aromaticity 0.0707

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4461.47

LogP -37.28

H-bond Donors 157.0

H-bond Acceptors 157.0

Rotatable Bonds 379.0

Heavy Atoms 793.0

Ring Count 16.0

Amide Bonds 109.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0191166 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence